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PERCOCET ( Oxycodone-Acetaminophen)
Health Conditions Medications Pain Percocet

PERCOCET ( Oxycodone-Acetaminophen)

Percocet is the brand name for the combination of Oxycodone and Acetaminophen. It is an effective painkiller and can offer you the energy to help you get through the day, especially when your pain is intolerable. Oxycodone is also an opioid pain medication. An opioid is sometimes called a narcotic. Acetaminophen is a less potent pain reliever that increases the effects of oxycodone. However, it should be taken with care because even taking Percocet as prescribed can get you addicted.


It should be individually quantified to minimize adverse reactions. The dose is adjusted according to severity of pain. But, you need to have a doctor’s advise for that. It may occasionally be necessary to exceed the usual dosage recommended in cases of more severe pain or in those patients who have become tolerant to the analgesic effect of opioids. If pain is constant, the opioid analgesic should be given at regular intervals on an around-the-clock schedule.

For Adults. Oxycodone 10 mg/acetaminophen 325 mg: 1 tablet orally every 6 hours as needed for pain
Maximum dose: 6 tablets in 24 hours

Percocet Side Effects

Get emergency medical help if you have signs of an allergic reaction to Percocet:

  • hives;
  • difficulty breathing;
  • swelling of your face, lips, tongue, or throat

Percocet can slow or stop your breathing, and death may occur. You should also seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing;
  • a light-headed feeling, like you might pass out;
  • weakness, tiredness, fever, unusual bruising or bleeding;
  • confusion, unusual thoughts or behavior;
  • problems with urination;
  • liver problems – nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • low cortisol levels  nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Serious side effects may be more likely in older adults and also to those who are overweight, malnourished, or debilitated.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. But, it is not known whether opioid effects on fertility are permanent.

Common Percocet side effects include:

  • dizziness, drowsiness, feeling tired;
  • feelings of extreme happiness or sadness;
  • nausea, vomiting, stomach pain;
  • constipation; or
  • Headache

Who should not take this medication?

People with the following should not take Oxycodone – acetaminophen :

  • has a seizure disorder
  • is allergic to oxycodone, acetaminophen, or to any of the ingredients of the medication
  • has preexisting respiratory depression
  • has status asthmaticus (unresponsive asthma)

Percocet Warnings and Precautions

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breastfeeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Abdominal conditions

Oxycodone may make the diagnosis of abdominal conditions more difficult or it may worsen these conditions. People with abdominal conditions such as inflammatory or obstructive bowel disease, acute cholecystitis, or pancreatitis should discuss with their doctor how this medication may affect their medical condition. And also, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Kidney function

People with kidney disease or reduced kidney function should discuss with their doctor how this medication may affect their medical condition. And how their medical condition affects the dosing and effectiveness of this medication, and whether it needs any special monitoring.

Liver function

Acetaminophen can cause decreased liver function. People with liver disease or reduced liver function should discuss with their doctor how this medication may affect their medical condition, and also how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.


This medication may cause seizures, especially when using higher doses. Or when using it with other medications that may increase the risk of seizures. The risk of seizures is also higher for people with epilepsy, a history of seizures, or who are at risk of seizures (e.g., people with head trauma).


This medication is not suitable during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.


This medication passes into breast milk. So, if you are a breastfeeding mother and are taking oxycodone and acetaminophen, it may affect your baby. Talk to your doctor about whether you should continue breastfeeding.

Most importantly, if you are taking any medications, speak with your doctor or pharmacist. Also, an interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how to manage any drug interactions. And if you have plans to buy Percocet online,  make sure to consider buying from your most trusted online pharmacies only.


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